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With any drug or medication you take, whether synthetic or natural, there may be advers oir side effects. The acnezine reviews state that some users mentioned some acnezine side effects. Most stated some tiredness as well as a “slight brain fog” shortly after taking the pills. The explanation is that acnezine forces your body to expel toxins that it has been holding for quite a while. The company states that the side effects should only last a few days, and that if you do experience them it is a sure sign that the treatment is working. The good new is that you should feel better after that initial period